Effects of organochlorine compounds on cytochrome P450 aromatase activity in an immortal sea turtle cell line     

Keller JM  McClellan-Green P 《Marine environmental research》2004,58(2-5):347-351

Many classes of environmental contaminants affect the reproductive function of animals through interactions with the endocrine system. The primary components affected by endocrine active compounds (EACs) are the steroid receptors and the enzymes responsible for steroidogenesis. This study sought to develop an in vitro model for assessing EAC effects in sea turtles by examining their ability to alter cytochrome P450 aromatase (CYP19) activity. Aromatase is the enzyme responsible for the conversion of testosterone to estradiol. This enzyme is critical in the sexual differentiation of reptiles which demonstrate temperature-dependent sex determination. An immortal testis cell line GST-TS from a green sea turtle was grown in culture at 30 degrees C in RPMI 1640 media. The cells were exposed to three known aromatase inducers; dexamethasone (Dex), 8Br-cyclic AMP, or human chronic gonadotropin (HCG) and one aromatase inhibitor 4-androstenol-dione (4-OHA). In addition, the GST-TS cells were exposed to 0.1-30 microM atrazine and 3-100 microM 4,4'-DDE. The inducing compounds that have been shown to increase aromatase activity in other systems failed to induce aromatase activity in the GST-TS cells, yet exposure to the inhibiting compound, 4-OHA, did result in a significant reduction. Atrazine (0.1, 1.0 and 10 microM) significantly induced aromatase activity following a 24 h exposure, and 4,4'-DDE inhibited the activity but only at cytotoxic concentrations (100 microM). Based on these results, this in vitro model can be useful in examining the endocrine effects of EACs in sea turtles.  相似文献   

Velocity-Interface Structure of the Southwestern Ryukyu Subduction Zone from EW9509-1 OBS/MCS Data     

Wang  Tan K.  McIntosh  Kirk  Nakamura  Yosio  Liu  Char-Shine  Chen  How-Wei 《Marine Geophysical Researches》2001,22(4):265-287

A wide-angle seismic survey, combining ocean-bottom seismometers (OBS) and multi-channel seismic (MCS) profiling, was implemented in the southwestern Ryukyu subduction zone during August and September 1995. In this paper, we present the data analysis of eight OBSs and the corresponding MCS line along profile EW9509-1 from this experiment. Seismic data modeling includes identification of refracted and reflected arrivals, initial model building from velocity analysis of the MCS data, and simultaneous and layer-stripping inversions of the OBS and MCS arrivals. The velocity-interface structure constructed along profile EW9509-1 shows that the northward subduction of the Philippine Sea Plate has resulted in a northward thickening of the sediments of the Ryukyu Trench and the Yaeyama accretionary wedge north of the trench. The boundary between the subducting oceanic crust and the overriding continental crust (represented by a velocity contour of 6.75 km/s) and a sudden increase of the subducting angle (from 5 degrees to 25 degrees) are well imaged below the Nanao Basin. Furthermore, velocity undulation and interface variation are found within the upper crust of the Ryukyu Arc. Therefore, the strongest compression due to subduction and a break-off of the slab may have occurred and induced the high seismicity in the forearc region. This revised version was published online in November 2006 with corrections to the Cover Date.  相似文献   

Type III radio burst productivity of solar flares     

M. PoquÉrusse  P. S. McIntosh 《Solar physics》1995,159(2):301-323

We study the occurrence probability of type III radio bursts during flares as a function of the flare position on the Sun. We find that this probability peaks around 30° east of the central meridian, which points to a reciprocal tilt of the average radiation pattern of type IIIs. We argue that anisotropic scattering of the radiation by overdense coronal fibers parallel to the magnetic field is the dominant factor determining the orientation of radiation patterns. It follows that the average magnetic field appears to be tilted 30° west from the vertical. We also find that within a given active region, the average type III production rate of flares peaks 1° west of the center of gravity of all the flares of this active region.We infer that the coronal magnetic field above active regions presents a strong east-west asymmetry, resulting from the well known asymmetry at the photospheric level. As the west side of an active region covers a smaller area with stronger magnetic field than the east side, western flares are generally closer to open field lines than eastern flares. As a consequence, accelerated particles on the trailing (east) side of active regions usually stay trapped in magnetic loops, while on the leading (west) side they are more likely to escape along open lines into interplanetary space. As a result of the initial westward tilt of these open lines, we estimate that the corresponding Archimedean spiral is on average (apparently) rooted 15° west of the flare.  相似文献   

Assessing Similarity of Geographic Processes and Events   总被引：6，自引：0，他引：6  

John McIntosh  May Yuan 《Transactions in GIS》2005,9(2):223-245

The increased availability of spatiotemporal data collected from satellite imagery and other remote sensors provides opportunities for enhanced analysis of geographic phenomena. Much of the new data includes regular snapshots of the environment. Comparison of these snapshots can provide information about changes to the phenomena of interest. However, conventional GIS data models and analytical tools lack capabilities to adequately handle massive multidimensional data. One of the fundamental tools necessary to meet such challenges is query support to retrieve and summarize data according to dynamic geographic phenomena, such as geographic events and processes, of interest. Such query support depends upon abilities to assess spatiotemporal similarity so that data representing geographic events that exhibit the spatiotemporal characteristics of interest can be identified in a GIS database. To this end, this paper introduces a method to assess similarity of geographic events and processes (such as storms) based on their spatiotemporal characteristics (such as distribution of precipitation). We developed six indices to capture static and dynamic characteristics of geographic events and applied the Dynamic Time Warping method to temporal sequences of the six indices to examine the similarity among these events. With a case study, we demonstrated the proposed indices and method capable of comparing spatiotemporal characteristics of events as recorded in a GIS database and categorizing spatiotemporal data into groups of events according to their behavior in space and time.  相似文献   

DISCUSSION     

Richelle M. Allen-King  Christene L. Albanese  Jennifer P. Martin 《Ground water》1997,35(6):1107-1109

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Use of Sequential Filtration for Determining Transportable Lead in Ground Water     

Renata Bailey  Joseph Marchesani  rew C. Marinucci  Jennifer Reynard  Paul Sanders 《Ground Water Monitoring & Remediation》2005,25(3):52-62

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Incorporating Spatial Dependence in Predictive Vegetation Models: Residual Interpolation Methods*     

Jennifer Miller 《The Professional geographer》2005,57(2):169-184

Predictive vegetation modeling can be used statistically to relate the distribution of vegetation across a landscape as a function of important environmental variables. Often these models are developed without considering the spatial pattern that is inherent in biogeographical data, resulting from either biotic processes or missing or misspecified environmental variables. Including spatial dependence explicitly in a predictive model can be an efficient way to improve model accuracy with the available data. In this study, model residuals were interpolated and added to model predictions, and the resulting prediction accuracies were assessed. Adding kriged residuals improved model accuracy more often than adding simulated residuals, although some alliances showed no improvement or worse accuracy when residuals were added. In general, the prediction accuracies that were not increased by adding kriged residuals were either rare in the sample or had high nonspatial model accuracy. Regression interpolation methods can be an important addition to current tools used in predictive vegetation models as they allow observations that are predicted well by environmental variables to be left alone, while adjusting over‐ and underpredicted observations based on local factors.  相似文献   

Importance of climate,forest fires and human population size in the Holocene boreal forest composition change in northern Europe          下载免费PDF全文

Niina Kuosmanen  Heikki Seppä  Teija Alenius  Richard H. W. Bradshaw  Jennifer l. Clear  Ludmila Filimonova  Maija Heikkilä  Hans Renssen  Miikka Tallavaara  Triin Reitalu 《Boreas: An International Journal of Quaternary Research》2016,45(4):688-702

The relative importance of climate, forest fires and human population size on long‐term boreal forest composition were statistically investigated at regional and local scales in Fennoscandia. We employ pollen data from lakes, reflecting regional vegetation, and small forest hollows, reflecting local vegetation, from Russia, Finland and Sweden to reconstruct the long‐term forest composition. As potential drivers of the Holocene forest dynamics we consider climate, generated from a climate model and oxygen isotope data, past forest fires generated from sedimentary charcoal data and human population size derived from radiocarbon dated archaeological findings. We apply the statistical method of variation partitioning to assess the relative importance of these environmental variables on long‐term boreal forest composition. The results show that climate is the main driver of the changes in Holocene boreal forest composition at the regional scale. However, at the local scale the role of climate is relatively small. In general, the importance of forest fires is low both at regional and local scales. The fact that both climate and forest fires explain relatively small proportions of variation in long‐term boreal vegetation in small forest hollow records demonstrates the complexity of factors affecting stand‐scale forest dynamics. The relative importance of human population size was low in both the prehistorical and the historical time periods. However, this is the first time that this type of data has been used to statistically assess the importance of human population size on boreal vegetation and the spatial representativeness of the data may cause bias to the analysis.  相似文献   

The relation of Holocene fluvial terraces to changes in climate and sediment supply,South Fork Payette River,Idaho     

Jennifer L. Pierce  Grant A. Meyer  Tammy Rittenour 《Quaternary Science Reviews》2011,30(5-6):628-645

Well-preserved Holocene terraces along the South Fork Payette River in central Idaho provide a record of fluvial system behavior in a steep mountain watershed characterized by weathered and erodible Idaho Batholith granitic rocks. Terrace deposit ages were provided by ¹⁴C dating of charcoal fragments and optically stimulated luminescence (OSL) dating of sandy sediments. Along with pairing of many terrace tread heights, these data indicate episodic downcutting during the Holocene, with a mean incision rate of ～0.9 m/ka from ～7 ka to present. Prior to 7 ka, the river incised to within～3 m of current bankfull, but then aggraded by ～5 m over at least a ～10 km-long reach in an episode centered ～7–6 ka. Aggradation may relate to (1) increased hillslope sediment input from landslides and debris flows in steep tributary basins with abundant grussified granitic bedrock, (2) possible local landslide-damming of the channel, (3) decreased peak discharge, or (4) a combination of these factors. Middle Holocene channel aggradation ca. 7–6 ka corresponds with a period of prolonged and widespread aridity in the northern Rocky Mountains. Between ～5 and 1.3 ka, the river aggraded slightly and then remained stable, forming a prominent terrace tread at ～3 m above current bankfull. Modest aggradation to vertical stability of the South Fork Payette River at the 1.5 m terrace level ～1.0–0.7 ka corresponds with large fire-related debris flows in tributaries during Medieval droughts. Three intervals of incision (～5.5–5 ka, 1.3–1.0 ka and 0.5 ka) correspond with frequent but small fire-related sedimentation events and generally cooler, wetter conditions suggesting increased snowmelt runoff discharges. Other possible drivers of channel incision include an increase in stochastic or climate-modulated large storms and floods and a reduction in delivery of hillslope sediment to the channel. Aggradation is more confidently tied to climate through increases in hillslope sediment delivery and (or) decreased stream power, both likely related to warmer, drier conditions (including high-severity fires) that reduce snowmelt and decrease vegetation cover on steep slopes. Thus, the Holocene terraces of the South Fork Payette River do not reflect simple stepwise incision with periods of vertical stability and lateral migration, but record substantial episodes of aggradation as well. We infer that increases in hillslope erosion and mass movements combined with reduced discharges during prolonged droughts episodically reverse the post-glacial trend of downcutting, in particular during the middle Holocene. The present bedrock-dominated channel implies a strong tendency toward incision in the late Holocene.  相似文献   

Modeling regional landslide susceptibility using dynamic soil moisture profiles     

Ram L. Ray  Jennifer M. Jacobs  Ellen M. Douglas 《山地科学学报》2018,15(8):1807-1824

A landslide susceptibility mapping study was performed using dynamic hillslope hydrology. The modified infinite slope stability model that directly includes vadose zone soil moisture (SM) was applied at Cleveland Corral, California, US and Krishnabhir, Dhading, Nepal. The variable infiltration capacity (VIC-3L) model simulated vadose zone soil moisture and the wetness index hydrologic model simulated groundwater (GW). The GW model predictions had a 75% NASH-Sutcliffe efficiency when compared to California’s in-situ GW measurements. The model performed best during the wet season. Using predicted GW and VIC-3L vadose zone SM, the developed landslide susceptibility maps showed very good agreement with mapped landslides at each study region. Previous quasi-dynamic model predictions of Nepal’s hazardous areas during extreme rainfall events were enhanced to improve the spatial characterization and provide the timing of hazardous conditions.  相似文献